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    Acute vs Chronic Inflammation

    Short-term inflammation is your body doing its job. This article explores the critical difference between healthy acute inflammation and the chronic low-grade kind that fails to resolve.

    Curated by the Red Road Wellness Research Team
    Missouri, USAAbout our editorial standards

    Inflammation gets a bad reputation, but the acute (short-term) kind is actually your body doing exactly what it should. When you cut your finger or catch a cold, the redness, warmth, swelling, and pain you experience are signs that your immune system has sprung into action. It is sending extra blood flow and immune cells to the area to fight off invaders and start healing.

    The important thing about this type of inflammation is that it has a built-in off switch. Your body produces special compounds, many of them made from omega-3 fats, that actively turn off the inflammatory response once the job is done. These compounds tell the fighter cells to stop arriving and tell cleanup crews to start removing debris and repairing tissue.

    Problems arise when inflammation does not turn off properly. Chronic (long-term) inflammation is a low-level, body-wide state where your immune system stays partially activated without a clear threat to fight. You might not even feel it directly, but blood tests can reveal elevated markers of inflammation in your body.

    Several lifestyle factors can keep your body stuck in this chronic inflammatory state: not enough sleep, too much stress, a diet heavy in processed foods and sugar, lack of physical activity, and excess body fat (especially around the midsection). These factors create cycles where inflammation feeds more inflammation, making it progressively harder for your body to calm down.

    The encouraging news is that the same lifestyle choices that contribute to chronic inflammation can be modified to support your body's natural ability to resolve it. Regular movement, stress-reducing practices, adequate sleep, and a diet rich in colorful fruits and vegetables, healthy fats, and fiber all support the pathways your body uses to bring inflammation back into balance.

    References & Citations

    1. [1]
      Serhan CN. Pro-resolving lipid mediators are leads for resolution physiology. Nature. 2014;510(7503):92-101.
    2. [2]
      Furman D, et al. Chronic inflammation in the etiology of disease across the life span. Nat Med. 2019;25(12):1822-1832.
    3. [3]
      Medzhitov R. Origin and physiological roles of inflammation. Nature. 2008;454(7203):428-435.

    This information is provided for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration.

    The Research in Practice

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